Int. J. Mol. Sci. 2010, 11, 4511-4525; doi:10.3390/ijms11114511 OPEN ACCESS international Journal of molecular Sciences ISSN 1422-0067 www.mdpi.com/ diary/ijms Review The Role of Molecular biological science in the Biomonitor of Human snatch to Chemicals Balam Muñoz and Arnulfo Albores * Departamento de ToxicologÃa, Centro de Investigación y de Estudios Avanzados del IPN, Av. IPN 2508, México, DF 07360, Mexico; e-mail: rbmunoz@cinvestav.mx * Author to whom unanimity should be addressed; E-Mail: aalbores@cinvestav.mx; Tel.: +52-55-50613308; Fax: +52-55-57477111. Received: 1 September 2010; in revise form: 12 October 2010 / sure enough: 29 October 2010 / Published: 12 November 2010 Abstract: Exposure to different substances in an occupational environment is of utmost concern to erratic agencies such as the area Health Organization and the world(prenominal) Labour Organization. Interest in improving work wellness conditions, particularly of those employees exposed to pernicious chemical substances, has increased well and has stirred the search for new, more than than specific and selective tests. Recently, the bowl of molecular biology has been indicated as an alternative technique for monitoring force play term evaluating work-related pathologies.
Originally, occupational exposure to environmental toxicantants was assessed using biochemical techniques to prepare the presence of higher concentrations of toxic compounds in blood, urine, or new(prenominal) fluids or tissues; results were used to respect potential wellness risk. However, this access code only estimates the presence of a noxious chemical and its effects, tho does not prevent or diminish the risk. Molecular biology methods have become real useful in occupational medicine to provide more accurate and well-timed(prenominal) diagnostics. In this review, we address the role of the following harsh techniques: (1) routine of cell cultures; (2) valuation of gene expression; (3) the omic sciences (genomics, transcriptomics, proteomics and...If you pauperism to grow a wide-cut essay, order it on our website:
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